عمرو عبدالمعز عبدالله

نبذة

التعليم

• Bachelor 2009
  6th October University, Faculty of Dentistry (Egypt)
  Oral and Dental Medicine
• Master Degree 2018
  Alexandria University, Faculty of Dentistry
  Oral Pathology
• PhD Degree 2025
  Alexandria University, Faculty of Dentistry
  Oral Pathology

السجل الوظيفي

• استاذ مساعد 2026 – 13/03/2014
  كلية طب الاسنان
  جامعة ابن سينا للعلوم الطبية
• مدرس 19/04/2025 – حتى الآن
  كلية طب الاسنان
  جامعة جنوب الوادي قنا مصر
• مدرس مساعد 02/08/2018 – 19/04/2025
  كلية طب الاسنان
  جامعة جنوب الوادي قنا مصر
• معيد 2014 – 02/08/2018
  كلية طب الاسنان
  جامعة جنوب الوادي قنا مصر
• معيد 2011 – 2014
  كلية طب الاسنان
  6أكتوبر مصر

أبحاث منشورة 4

• EXPRESSION OF ARGYROPHILIC NUCLEOLAR ORGANIZING REGION COUNTS AND PROLIFERATING CELL NUCLEAR ANTIGEN IN EPITHELIAL ODONTOGENIC TUMORS
  Odontogenic tumors are diverse groups of lesions derived from odontogenic tissues. Clinical behavior of these lesions varies widely, ranging from benign to malignant with differences in recurrence rate and growth pattern. Abetter understanding of the underlying molecular mechanisms will help to predict the course of odontogenic tumors and lead to the development of new therapeutic applications. Nucleolar organizer regions (NORs) are loops of DNA that codify the ribosomal RNA and are considered important for protein synthesis. The NORs stained histochemicaly by silver are named argyrophilic nucleolar organizer regions (AgNOR). Quantification of AgNOR represents a valuable parameter of cell kinetics and therefore cell proliferation. The number of AgNOR sites in malignant cells is significantly greater than those in their normal or benign counterparts. Proliferating cell nuclear antigen (PCNA) is a useful marker of cellular proliferation and DNA replication. Malignant tissue is characterized by an uncoordinated proliferating cell nuclear antigen (PCNA).
• EVALUATION OF SALVIA ROSMARINUS AND CORIANDRUM SATIVUM AS CHEMOPREVENTIVE AGENTS IN INDUCED ORAL SQUAMOUS CELL CARCINOMA (AN EXPERIMENTAL STUDY)
  The most prevalent malignant tumor of the head and neck region is squamous cell carcinoma. The bad prognosis and low survival rate are mainly related to oral cancer patients. Developing chemopreventive techniques has been crucial to reduce the incidence of oral cancer. Chemoprevention with natural products has emerged as viable preventive options. Salvia rosmarinus and Coriandrum sativum have been studied and discovered to have powerful anticancer properties. Aim of the study The present trial was proceeded to study the effects of salvia rosmarinus and coriandrum sativum during experimental hamster buccal pouch carcinoma induction; using PCNA as cancer proliferative cell marker. Material and Methods A total of 60 adult male hamsters were divided into 5 equal groups. Group I, biopsies of normal pouch mucosa were obtained as a negative control. All remaining groups were painted by DMBA as a carcinogenic agent. Group II, as a positive control group, was only painted by DMBA. Group III received topically salvia rosmarinus oil. Group IV received topically coriandrum sativum oil. Group V received both oils together. After 16, 24, and 32 weeks, 2 to 4 animals from every group had been sacrificed. Tissue lesions were prepared, and paraffin sections were stained with primary antibody for PCNA immunohistochemical evaluation. Results The salvia rosmarinus and coriandrum sativum; either alone or in combination, significantly reduced the carcinogenic effect for DMBA-induced oral carcinogenesis. Conclusion Salvia rosmarinus and coriandrum sativum have a chemopreventive considerable action versus oral cancer …
• CLINICAL FINDINGS OF BASAL CELL NEVUS SYNDROME
  AbstractBackground Basal cell nevus syndrome or Gorlin syndrome is a rare genetic autosomal dominant disorder associated with different neoplasms that may be aggressive with further aging so that earlier diagnosis of this syndrome is crucialAim of the study The aim of this study is to present different clinical pictures and diagnostic means to facilitate identification of patients affected by basal cell nevus bifid rib syndrome Subject and methods Seven patients presented with basal cell nevus syndrome were investigated through reporting medical and dental history, clinical and radiological examinations, histopathological investigations , routine laboratory investigations and referral to different specialties as dermatology , neurosurgery and orthopedics .Results All the patients presented with odontogenic keratocysts , bifid ribs, skin nevi, and skeletal disorders .. with three patients having family history affected by the same findings .Conclusionbasal cell nevus bifid rib syndrome has different clinical presentations and many specialists of different specialties as maxillofacial surgery, neurosurgery , dermatology and others must be aware of them ,also affected patients need frequent, follow up to avoid any complications associated with this syndrome ..
• Calcifying odontogenic cyst mimicking endodontic pathology: a case of unnecessary endodontic treatment of vital teeth
  Calcifying Odontogenic Cyst (COC) is a rare developmental odontogenic lesion that may present as a periapical radiolucency, mimicking inflammatory pathology and posing a diagnostic challenge. Case presentation: In this report, a 17-year-old female patient was referred to an oral surgery practice with a history of recurrent swelling and pain in the anterior mandible. Teeth 31, 41, and 42 (according to the FDI International two-digit system) had been endodontically treated by the referring dentist prior to referral. Clinical examination revealed a localized labial swelling without signs of acute infection. A panoramic radiograph provided with the referral demonstrated a well defined unilocular periapical radiolucency extending across the mandibular incisors. The initial management by the general dental practitioner was based primarily on radiographic findings, without documented pulp vitality testing, leading to root canal treatment of multiple teeth prior to specialist referral. Following referral, an incisional biopsy was performed, and histopathological analysis revealed a cystic lesion lined by ameloblastomatous-type odontogenic epithelium with characteristic ghost cells and calcifications, confirming the diagnosis of a calcifying odontogenic cyst. The lesion was surgically enucleated, and one-year follow-up showed complete healing with no recurrence. Conclusion: This case highlights the diagnostic challenges associated with non-endodontic periapical lesions and emphasizes the critical importance of pulp vitality testing, careful radiographic interpretation, and timely specialist referral to avoid unnecessary and irreversible dental treatment